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Mehdi Kushkestani,Mohsen Parvani, Shiva Ebrahimpour Nosrani, Sohrab Rezaei, Maryam Karimi


Department of Physiology, Faculty of Physical Education and Sport Sciences, Allameh Tabataba’i University, Tehran1485743411, Iran


Purpose:The aim of this study was to investigate lipid profile and hepatic enzymes difference between pre-diabetes and normal subjects.Methods:In this cross-sectional study, 264 employees of Energy Industries Engineering & Design (EIED) Company were randomly selected and participated in the study in January 2019.A sample of 10 mL of venous blood was obtained between 8 a.m. and 10 a.m. Blood analyses for fasting glucose (FG), total cholesterol (TC), triglyceride (TG), LDL-cholesterol, HDL-cholesterol, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) levels were determined by enzymatic methods. Body composition and anthropometric indices were measured and recorded using the OMRON BF511 device and tape measure.Achievements of This Study:TG, the LDL/HDL ratio, and the ALT were significantly higher in the pre-diabetes group. Also, body mass index, waist circumference, waist-hip ratio were significantly higher in pre-diabetic women than in normoglycemic women.According to the results of this study suggested that the risk of cardiovascular and liver diseases in people with pre-diabetes increases and the intervention of lifestyle such as increased levels of physical activity and exercise to prevent diabetes and related complications.


Diabetes, aged, liver disease, exercise, physical activity.

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