Paper Status Tracking

Journals by Title

Journals by Subject

Contact us

	[email protected]
	3275638434

	Paper Publishing WeChat

Useful Links

Creative Commons Attribution-NonCommercial 4.0 International License

Article

Open Access

Synthesis of Iridium(III) Complex Bearing 1-Thio-β-D-glucose Tetraacetate Moieties and its Photogeneration of Singlet Oxygen

Author(s)

Keisuke Fukumoto¹, Keisuke Hyakumura¹, Akinori Murata¹, Yuta Sakai¹, Shigenobu Yano², Akihiro Nomoto^1*, Suguru Miyashita³, Atsushi Narumi³ and Akiya Ogawa¹

Full-Text PDF Download XML 784 Views

DOI:10.17265/2161-6213/2016.11-12.001

Affiliation(s)

1. Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, 1-1 Gakuen-cho, Nakaku, Sakai, Osaka 599-8531, Japan
2. Graduate School of Material Science, Nara Institute of Science and Technology, 8916-5,Takayama-cho,Ikoma, Nara 630-0192, Japan
3. Department of Organic Materials Science, Graduate School of Organic Materials Science, Yamagata University, Jonan 4-3-16, Yonezawa 992-8510, Japan

ABSTRACT

Investigation of effective photodynamic therapy (PDT) reagents needs to observe ¹O₂. The observation of the amount of photogenerated ¹O₂ emission at 1,270 nm is one of the engaged method for ¹O₂ generation evolution quantitatively, however it is convenient to observe fluorescent spectra relevant to a phosphorescence of singlet molecular oxygen due to the energy transfer from PDT reagents to ³O₂. Ir(III) complex containing a thioglucose tetraacetate-conjugated bipyridyl ligand were synthesized newly, and the photogeneration of ¹O₂ was confirmed by measurement of a phosphorescence of singlet molecular oxygen.

KEYWORDS

Photosensitizer, photodynamic therapy (PDT) reagents, singlet oxygen, glucose, iridium(III) complex, warburg effect.

Cite this paper

References

Synthesis of Iridium(III) Complex Bearing 1-Thio-β-D-glucose Tetraacetate Moieties and its Photogeneration of Singlet Oxygen

Keisuke Fukumoto1, Keisuke Hyakumura1, Akinori Murata1, Yuta Sakai1, Shigenobu Yano2, Akihiro Nomoto1*, Suguru Miyashita3, Atsushi Narumi3 and Akiya Ogawa1

Keisuke Fukumoto¹, Keisuke Hyakumura¹, Akinori Murata¹, Yuta Sakai¹, Shigenobu Yano², Akihiro Nomoto^1*, Suguru Miyashita³, Atsushi Narumi³ and Akiya Ogawa¹